Publications

2025

Baltramonaityte V, Karhunen V, Felix JF, Penninx BWJH, Cecil CAM, Fairchild G, Milaneschi Y & Walton E, on behalf of the EarlyCause Consortium (2025). Biological pathways underlying the relationship between childhood maltreatment and multimorbidity: A two-step, multivariable Mendelian randomisation study. Brain, Behavior, and Immunity.
Bigler ME, Schuurmans IK, Zhu Y, Siddique N, Hoffman N, Koen N, Zar HJ, Stein DJ, Cecil CAM & Dunn EC (2025). Are different types of childhood adversities correlated within and across time? A comparison of data on adversity co-occurrence from three longitudinal birth cohort studies. Child Abuse & Neglect.
Creasey N, Schuurmans I, Tsotsi S, Defina S, Baltramonaityte V, Felix JF, Neumann A, Page CM, Tollenaar M, Bekkhus M, Walton E & Cecil CAM (2025). Prenatal stress, epigenetically-assessed glucocorticoid exposure at birth, and child psychiatric symptoms: A prospective, multi-cohort study. Psychoneuroendocrinology.
Defina S, Cecil CAM, Felix JF, Walton E & Tiemeier H (2025). Longitudinal co-development of mental and cardio-metabolic health from childhood to young adulthood. Journal of Child Psychology and Psychiatry.
Gigase FAJ, Suleri A, Isaevska E, Rommel A, Boekhorst MGB, Dmitrichenko O, el Marroun H, Steegers EAP, Hillegers MHJ, Muetzel RL, Lieb W, Cecil CAM, Pop VJM, Breen M, Bergink V & de Witte L (2025). Inflammatory markers in pregnancy – identifying drivers in four large cohorts. Frontiers in Immunology.
Guo X, Sulaiman M, Neumann A, Zheng SC, Cecil CAM, Teschendorff A & Heijmans B (2025). Unified high-resolution immune cell fraction estimation in blood tissue from birth to old age. Genome Medicine.
Guo X, Robertson JA, Aparicio A, Seale K, Chen Q, Richmond A, Du Z, Sulaiman M, Zheng SC, Ballestar E, Cecil CAM, Heijmans BT, Horvath S, Dwaraka VB, Lasky-Su J, Smith R, Marioni RE & Teschendorff AE (2025). Variations in innate immune cell subtypes correlate with epigenetic clocks, inflammaging and health outcomes. Advanced Science.
Kuilman M, Finke T, Ikram AM, Luik A, Neumann A, Cecil CAM & Ghanbari M (2025). Plasma circulating microRNAs and symptoms of depression: Results from a population-based study. Psychiatry and Clinical Neurosciences.
Larose M, Schuurmans I, Barker ED, Mondragon LG, Tiemeier H, Waldman I & Cecil CAM (2025). Associations between genetic predisposition to mental health problems and academic achievement: A developmental perspective using two population-based cohorts. Journal of Child Psychology and Psychiatry.
Layinka O, Souama C, Defina S, Baltramonaityte V, Cecil CAM, Shah P, Milaneschi Y, Lamers F, Penninx BWJH & Walton E (2025). Lifestyle behaviours do not moderate the association between childhood maltreatment and comorbid depression and cardiometabolic disease: A meta-analysis. BMC Medicine.
Meijer M, Klein M, Caramaschi D, Clark SL, Cosin-Tomas M, Koen N, Lu X, Mulder RH, Röder SW, Zhang Y, Zilich L, Bustamente M, Deuschle M, Felix JF, Ramos González J, Gražulevičiene R, Streit F, Wright J, Carracedo A, Cecil CAM, Corpeleijn E, Hartman CA, Herberth G, Huels A, Relton C, Snieder H, Stein DJ, Sunyer J, Witt SH, Zar HJ, Zenclussen AC, Franke B & van den Oord EJC (2025). Cell type-specific methylome-wide association studies of childhood ADHD symptoms. European Neuropsychopharmacology.
Mulder RH, Baltramonaityte V, Defina S, Trajanoska K, Suderman M, Schwarz E, Boks MPM, Walton E, Cecil CAM & Felix JF (2025). Interactive effects of genotype with prenatal stress on DNA methylation at birth. Molecular Psychiatry.
Neumann A, Sammallahti S, Cosin-Tomas M, Reese SE, Suderman M, Alemany S, Almqvist C, Andrusaityte S, Arshad SH, Bakermans-Kranenburg MJ, Beilin L, Breton C, Bustamante M, Czamara D, Dabelea D, Eng C, Eskenazi B, Fuemmeler BF, Gilliland FD, Grazuleviciene R, Håberg SE, Herberth G, Holland N, Hough A, Hu D, Huen K, Hüls A, Jin J, Julvez J, Koletzko BV, Koppelman GH, Kull I, Lu X, Maitre L, Mason D, Mélen E, Merid SK, Molloy PL, Mori TA, Mulder RH, Page CM, Richmond RC, Roder S, Ross JP, Schellhas L, Sebert S, Sheppard D, Snieder H, Starling AP, Stein DJ, Tindula G, van IJzendoorn MH, Vonk J, Walton E, Witonsky J, Xu CJ, Yang IV, Yousefi PD, Zar HJ, Zenclussen AC, Zhang H, Tiemeier H, London SJ, Felix JF & Cecil CAM (2025). Epigenetic timing effects on child developmental outcomes: A longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium. Genome Medicine.
Ngoc Dang V, Cecil CAM, Pariante C, Hernandez-Gonzalez J & Lekadir K (2025). Characterizing the role of early life factors in machine learning-based multimorbidity risk prediction. PLOS Digital Health.
Runze J, van IJzendoorn MH, Witte AM, Cecil CAM & Bakermans-Kranenburg MJ (2025). Intergenerational transmission of attachment: The role of intelligence. JCPP Advances.
Sanders F, Baltramonaityte V, Donohoe G, Davies N, Dunn EC, Cecil CAM & Walton E (in press). Associations between epigenetic age and brain age in young people. Scientific Reports.
Schuurmans IK, Mulder RH, Baltramonaityte V, Lahtinen A, Qiuyu F, Rothmann LM, Staginnus M, Tuulari J, Burt SA, Buss C, Craig JM, Donald KA, Eriksson JG, Felix JF, Freeman TP, Grassi-Oliveira R, Huels A, Hyde LW, Jones SA, Karlsson H, Karlsson L, Koen N, Lawn W, Mitchell C, Monk CS, Mooney MA, Muetzel R, Nigg JT, Belangero SIN, Notterman D, Ong YY, O’Connor T, O’Donnell KJ, Pan PM, Paunio T, Ryabinin P, Saffery R, Salum GA, Seal M, Silk TJ, Stein DJ, Tan AP, Teh AL, Wang D, Zar H, Walton E & Cecil CAM (2025). Consortium profile: The Methylation, Imaging and NeuroDevelopment (MIND) Consortium. Molecular Psychiatry.
Souama C, Milaneschi Y, Lamers F, Vinkers CH, Baltramonaityte V, Defina S, Garvert L, Cecil CAM, Felix JF, Galenkamp H, Grabe HJ, Lok A, Kok AAL, Molendijk M, Mulders AGMGJ, Oude Voshaar RC, Rhebergen D, Van Der Wee NJA, Völzke H, Walton E & Penninx BWJH, on behalf of the EarlyCause Consortium (2025). The association of childhood maltreatment, depression and their combination with adiposity and dyslipidaemia: An individual participant data meta-analysis. Psychological Medicine.
Townend S, Staginnus M, Gao Y, Alexander N, Arolt V, […] Cecil CAM, Aghajani M, Pine DS, van der Wee NJA, Stein DJ, Groenewold NA, Bas-Hoogendam JM, Han LKM, Pozzi E, Schmaal L, Franke B, Hoogman M, Walton E, De Brito SA & Fairchild G, on behalf of the ENIGMA Antisocial Behavior, Anxiety, ADHD, and MDD Working Groups (2025). Shared and distinct alterations in brain structure of youth with internalizing or externalizing disorders: Findings from the ENIGMA Antisocial Behavior, ADHD, MDD, and Anxiety Working Groups. Biological Psychiatry.
Van der Laan CM, Ip HF, Schipper M, Hottenga JJ, St Pourcain B, […] Cecil CAM […] Boomsma DI (2025). Meta-analysis of genome-wide association studies on childhood ADHD symptoms and diagnosis reveals 17 novel loci and 22 potential effector genes. Nature Genetics.
Zarchev M, Gigase FAJ, de Witte L, Cecil CAM, Hillegers MHJ, Ospina LH, Suleri A, Rommel A, Muetzel RL & Bergink V (2025). Maternal infection – but not inflammation – is associated with attention-deficit/hyperactivity disorder symptoms during childhood: a population-based cohort study. Brain, Behavior, and Immunity.

2024

Defina S, Vincente Silva CS, Cecil CAM, Tiemeier H, Felix JF, Muetzel R & Jaddoe VWV (2024). Associations of arterial thickness, stiffness and blood pressure with brain morphology in early adolescence: A prospective population-based study. Hypertension. https://doi.org/10.1161/hypertensionaha.123.21672

Defina S, Woofenden T, Baltramonaityte V, Pariante CM, Lekadir K, Jaddoe VWV, Serdarevic F, Tiemeier H, Walton E, Felix JF, & Cecil CAM (2024). Differential effects of prenatal and postnatal ELS on internalizing symptoms, adiposity and their comorbidity in early adolescence. JAACAP. 10.1016/j.jaac.2023.05.034

Defina S, Woofenden T, Baltramonaityte V, Tiemeier H, Fairchild G, Felix JF, Cecil CAM & Walton E (2024). The role of lifestyle factors in the association between early-life stress and adolescent physical and mental health. Preventive Medicine.

Gao Y, Staginnus M, Townend S, Arango C, Bajaj S et al (2024). Cortical structure and subcortical volumes in conduct disorder: A coordinated analysis of 15 international cohorts from the ENIGMA Antisocial Behavior working group. Lancet Psychiatry. https://doi.org/10.1016/S2215-0366(24)00187-1

Goncalves R, Guaillard R, Cecil CAM, Defina S, Steegers EAP & Jaddoe VWV (2024). Arterial health markers in relation to behavior and cognitive outcomes at school-age. Journal of the American Heart Association. https://doi.org/10.1161/jaha.123.029771.

Knol, M. J., Poot, R. A., Evans, T. E., Satizabal, C. L., Mishra, A., et al (2024). Genetic variants for head size share genes and pathways with cancer. Cell Reports Medicine, 5(5). https://doi.org/10.1016/j.xcrm.2024.101529.

Korologou-Linden R, Shuurmans I, Cecil CAM, White T, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Brühl R, Martinot JL, Paillère Martinot ML, Artiges E, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Millenet S, Fröhner JH, Smolka M, Walter H, Whelan R, Schumann G, Howe LD, Ben-Shlomo Y, Davies NM, Anderson EL (2024). Genetics impact risk of Alzheimer’s disease through mechanisms modulating structural brain morphology in late life. Journal of Neurology, Neurosurgery, and Psychiatry.

Lussier AA, Smith BJ, Fischer J, Luo M, Cerutti J, Schneper L, Smith T, Cecil CAM, Felix JF, Mitchell C, Notterman DA, Ressler KJ, Schaid DJ, Simpkin AJ, Suderman MJ, Walton E, Smith ADAC, Dunn EC (2024). DNA methylation may partially explain the relationship between childhood adversity and depressive symptoms in adolescence. Nature Mental Health.

Mulder RH, Kraaij R, Schuurmans IK, Frances-Cuesta C, Sanz Y, Medina-Gomez C, Duijts L, Rivadeneira F, Tiemeier H, Jaddoe VWV, Felix JF & Cecil CAM (2024). Early-life stress and the gut microbiome: A comprehensive population-based investigation. Brain Behavior and Immunity. https://doi.org/10.1016/j.bbi.2024.02.024.

Mulder RH, Neumann A, Felix JF, Suderman M & Cecil CAM (2024). Characterizing developmental dynamics of adult epigenetic clock sites. eBioMedicine. 10.1016/j.ebiom.2024.105425.

Neumann A, Sammallahti S, Cosin-Tomas M, Reese SE, Suderman M, Alemany S, Almqvist C, Andrusaityte S, Arshad SH, Bakermans-Kranenburg MJ, Beilin L, Breton C, Bustamante M, Czamara D, Dabelea D, Eng C, Eskenazi B, Fuemmeler BF, Gilliland FD, Grazuleviciene R, Håberg SE, Herberth G, Holland N, Hough A, Hu D, Huen K, Hüls A, Jin J, Julvez J, Koletzko BV, Koppelman GH, Kull I, Lu X, Maitre L, Mason D, Mélen E, Merid SK, Molloy PL, Mori TA, Mulder RH, Page CM, Richmond RC, Roder S, Ross JP, Schellhas L, Sebert S, Sheppard D, Snieder H, Starling AP, Stein DJ, Tindula G, van IJzendoorn MH, Vonk J, Walton E, Witonsky J, Xu CJ, Yang IV, Yousefi PD, Zar HJ, Zenclussen AC, Zhang H, Tiemeier H, London SJ, Felix JF, Cecil CAM (Preprint). Epigenetic timing effects on child developmental outcomes: A longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium. medRxiv. doi: https://doi.org/10.1101/2024.02.29.24303506

Ngoc Dang V, Cascarano A, Mulder RH, Cecil CAM, Zuluaga MA, Hernandez-Gonzalez J & Lekadir K (2024). Fairness and bias correction in machine learning for depression prediction: results from four study populations. Scientific Reports. https://doi.org/10.1038/s41598-024-58427-7.

Salontaji K, Hafton KL, Sanders F, Page CM, Walton E, Felix JF, Bekkus M, Bohlin J, Tiemeier H & Cecil CAM (2024). Gestational epigenetic age and ADHD symptoms in childhood:A prospective, multi-cohort study. Molecular Psychiatry.

Suleri A, Creasey N, Walton E, Muetzel R, Felix JF, Duikts L, Bergink V & Cecil, CAM (2024). Mapping prenatal predictors and neurobehavioral outcomes of an epigenetic marker of neonatal inflammation: A longitudinal population-based study. Brain, Behavior & Immunity. https://doi.org/10.1016/j.bbi.2024.08.053.

Suleri A, Gaiser C, Cecil CAM, Dijkzeul A, Neumann A, Labreque JA, … & Muetzel, RL (2024). Examining longitudinal associations between prenatal exposure to infections and child brain morphology. Brain, Behavior, and Immunity. https://doi.org/10.1016%2Fj.bbi.2024.05.014.

Suleri A, Rommel A, Dmitrichenko O, Muetzel RL, Cecil CAM, de Witte L & Bergink V (2024). The Association Between Maternal Immune Activation and Brain Structure and Function in Human Offspring: A Systematic Review. Molecular Psychiatry. https://doi.org/10.1038/s41380-024-02760-w.

Suleri A, White T, de Witte L, Gigase F, Cecil CAM, Jaddoe VWV, Breen M, Hillegers MHJ, Muetzel RL, & Bergink V (2024). Maternal immune activation and child brain development: a longitudinal population-based multimodal neuroimaging study. Biological Psychiatry – Cognitive Neuroscience and Neuroimaging. https://doi.org/10.1016/j.bpsc.2024.10.013.

Suleri A, Salontaji K, Luo M, Neumann A, Mulder RH, Tiemeier H, Felix JF, Marioni RE, Bergink V, Cecil CAM (2024). Prenatal exposure to common infections and newborn DNA methylation: A prospective, population-based study. Brain, Behavior, and Immunity. https://doi.org/10.1016/j.bbi.2024.07.046.

van Houtum LAEM, Baaré WFC, Beckmann CF, Castro-Fornieles J, Cecil CAM, Dittrich J, Ebdrup BH, Fegert JM, Havdahl A, Hillegers MHJ, Kalisch R, Kushner SA, Mansuy IM, Mežinska S, Moreno C, Muetzel RL, Neumann A, Nordentoft M, Pingault JB, Preisig M, Raballo A, Saunders J, Sprooten E, Sugranyes G, Tiemeier H, van Woerden GM, Vandeleur CL, van Haren NEM (2024). Running in the FAMILY – understanding and predicting the intergenerational transmission of mental illness. European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-024-02423-9.

2023

Baltramonaityte V, Pingault JB, Cecil CAM, Choudhary P, Järvelin MR, Penninx BWJH, Felix J, Sebert S, Milaneschi Y & Walton E, on behalf of the EarlyCause Consortium (2023). A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity. PLOS Genetics. https://doi.org/10.1371/journal.pgen.1010508

Cecil CAM & Schuurmans IK (2023). On navigating analytical choices in research on early life adversity: A commentary on Sisitsky et al. (2023). Research on Child and Adolescent Psychopathology. https://doi.org/10.1007/s10802-023-01103-7

Dang VN, Cascarano A, Mulder RH, Cecil CAM, Zuluaga MA, Hernandez-Gonzalez J & Lekadir K (2023). Fairness and bias correction in machine learning for depression prediction: results from four different study populations. arXiv. https://arxiv.org/abs/2211.05321

de Graaf I, Bolhuis K, Cecil CAM, White T & van Dongen S (2023). Child neuropsychological functioning and interpersonal callousness as predictors of externalising behaviour in early adolescence: A prospective population-based study. Research on Child and Adolescent Psychopathology. https://doi.org/10.1007/s10802-023-01091-8

Hoepel SJW, Schuurmans IK, CAM Cecil, Jaddoe VWV & Luik AI (2023). Life stress and adiposity in mothers: a 14-year follow-up in the general population. Stress and Health. https://doi.org/10.1002/smi.3290

Hughes DE, Kunitoki K, Elyounssi S, Luo M, Bazer OM, Hopkinson CE, Dowling KF, Doyle AE, Dunn E, Eryilmaz H, Gilman JM, Holt DJ, Valera EM, Smoller JW, Cecil CAM, Tiemeier H, Lee PH & Roffman JL (2023). Genetic Patterning for Child Psychopathology is Distinct from that for Adults and Implicates Fetal Cerebellar Development. Nature Neuroscience. https://doi.org/10.1038/s41593-023-01321-8

Kraaij R, Schuurmans IK, Radjabzadeh D, Tiemeier H, Dinan TG, Uitterlinden AG, Hillegers M, Jaddoe VWV, Duijts L, Moll H, Rivadeneira F, Medina-Gomez C, Jansen PW, Cecil CAM (2023). The gut microbiome and child mental health: a population-based study. Brain, Behavior and Immunity., DOI: 10.1016/j.bbi.2022.12.006.

Kotsakis Ruehlmann A, Sammallahti S, Cortes Hidalgo AP, Bakulski KM, Binder EB, Campbell ML, Caramaschi D, Cecil CAM, et al., (2023). Epigenome-Wide Meta-Analysis of Prenatal Maternal Stressful Life Events and Newborn DNA Methylation. Molecular Psychiatry. DOI: https://doi.org/10.1038/s41380-023-02010-5.

Luo M, Walton E, Neumann A, Thio CHL, Felix JF, van Ijzendoorn MH, Pappa I & Cecil CAM (2023). DNA Methylation at Birth and Lateral Ventricular Volume in Childhood: A Neuroimaging Epigenetics Study. JCPP. DOI: 10.1111/jcpp.13866

Schuurmans IK, Hoepel S, Cecil CAM, Hillegers MHJ, Ikram MA & Luik AI (2023). The association of life stress with subsequent brain and cognitive reserve in middle-aged women. Journal of Alzheimer’s Disease. DOI: 10.3233/JAD-220923

Schuurmans IK, Lamballais S, Zou R, Muetzel RL, Hillegers MHJ, Cecil CAM & Luik AI (2023). 10-year trajectories of depressive symptoms and subsequent brain health in middle-aged adults. Journal of Psychiatric Research. DOI: 10.1016/j.jpsychires.2022.12.018

Serdarevic F, Luo M, Karabegović I, Binter A, Alemany S, Mutzel R, Guxens M, Bustamante M, Hajdarpasic A, White T, Felix JF, Cecil CAM & Tiemeier H (2023). DNA Methylation at Birth and Fine Motor Ability in Childhood: An Epigenome-wide Association Study with Replication. Epigenetics. DOI: 10.1080/15592294.2023.2207253

Souama C, Lamers F, Milaneschi Y, Vinkers CH, Defina S et al (2023). Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment: an individual participant data meta-analysis including over 200,000 participants. BMC Medicine. DOI: https://doi.org/10.1186/s12916-023-02769-y.

Suleri A, Cecil CAM, Rommel A, Hillegers M, White T, de Witte L, Muetzel RL & Bergink (In Press). Long-term effects of prenatal infection on the human brain: a prospective multimodal neuroimaging study. Translational Psychiatry.

Suleri A, Rommel A, Neumann A, Luo M, Hillegers M, de Witte L, Bergink V & Cecil CAM (In Press). Exposure to prenatal infection and the development of internalizing and externalizing problems in children: A longitudinal population-based study. JCPP.

Suleri A, White T, Blok E, Cecil CAM, Reiss I, Jaddoe VWV, Gigase F, Hillegers M, de Witte L, Bergink V & Rommel A (2023). The Association Between Prenatal Infection and Adolescent Behavior: Investigating Multiple Prenatal, Perinatal, and Childhood Second Hits. JAACAP. DOI: 10.1016/j.jaac.2023.06.009

Walton E, Baltramonaityte V, Calhoun V, Heijmans B, Thompson P & Cecil CAM (2023). A systematic review of neuroimaging epigenetic research: Calling for an increased focus on development. Molecular Psychiatry. DOI: 10.1038/s41380-023-02067-2

2022

Bolhuis K, Steenkamp LR, Tiemeier H, Blanken L, Pingault JB, Cecil CAM & El Marroun H (2022). A prospective cohort study on the intergenerational transmission of childhood adversity and subsequent risk of psychotic experiences in adolescence. Schizophrenia Bulletin.

Bolhuis K, Mulder RH, de Mol CL, Defina S, Warrier V, White T, Tiemeier H, Muetzel RL & Cecil CAM (2022). Mapping gene by early life stress interactions on child subcortical brain structures: A genome-wide prospective study. JCPP Advances. DOI: https://doi.org/10.1002/jcv2.12113.

Caramaschi D*, Neumann A*, Lahti JMT, Cardenas A, Tindula G…Cecil CAM & Sharp G (2022). Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive abilities. Molecular Psychiatry. DOI: https://doi.org/10.1038/s41380-022-01441-w.

Cecil CAM, Neumann A & Walton E (2022). Epigenetics applied to child and adolescent mental health: Progress, challenges and opportunities. Invited review. JCPP Advances. DOI: 10.1002/jcv2.12133.

Cecil CAM & Nigg JT (2022). Epigenetics and ADHD: Reflections on current knowledge, research priorities and translational potential. Invited Current Opinion. Molecular Diagnosis & Therapy. DOI: 10.1007/s40291-022-00609-y

Marchi M, Elkrief L, Alkema A, van Gastel W, Schubart CD, van Eijck K, Luykx JL, Branje S, Mastrothedoros S, Galeazzi GM, van Os J, Cecil CAM, Conrod PJ & Boks MP (2022). Childhood maltreatment mediates the effect of the genetic background on psychosis risk in young adults. Translational Psychiatry. DOI: https://doi.org/10.1038/s41398-022-01975-1.

Neumann, A., Pingault, JB, Felix JF, Jaddoe VWV, Tiemeier H, Cecil CAM* & Walton E* (2022). Epigenome-wide contributions to individual differences in childhood phenotypes: A GREML approach. Clinical Epigenetics. DOI: 10.1186/s13148-022-01268-w.

Rijlaarsdam J, Cosin C, Schellhas L, Abrishamcar S, Malmberg A, … Caramaschi D, Alemany S, Cecil CAM (2022). DNA methylation and general psychopathology in childhood: An epigenome-wide meta-analysis from the PACE consortium. Molecular Psychiatry. DOI: https://doi.org/10.1038/s41380-022-01871-6.

Sammallahti S, Koopman-Verhoeff E, Binter A, Mulder R, Cabré-Riera A…Guxens M, Richmond RC & Cecil CAM (2022). Longitudinal associations of DNA methylation and sleep in children: A meta-analysis. Clinical Epigenetics. DOI: https://doi.org/10.1186/s13148-022-01298-4.

Schuurmans IK, Luik AI, de Maat DA, Hillegers MHJ, Ikram MA & Cecil CAM (2022). The association of early life stress with IQ-achievement discrepancy in children: A population-based study. Child Development. DOI: 10.1111/cdev.13825.

Schuurmans IK, Tamayo Martinez N, Blok E, Hillegers MHJ, Ikram MA, Luik AI & Cecil CAM (2022). Child mental health problems as a risk factor for academic underachievement: a multi-informant, population-based study. Acta Psychiatrica Scandinava. DOI: https://doi.org/10.1111/acps.13426. Epub ahead of print.

Verhoef, E., Allegrini, A. G., Jansen, P. R., Lange, K., Wang, C. A., Morgan, A. T., … & EAGLE working group. (2022). Genomic contributions to infant and toddler vocabulary scores: Implications for association with health-, cognition-and behaviour-related outcomes. bioRxiv. DOI: https://doi.org/10.1101/2022.06.01.494306.

Vieira R, Pires PP, Cecil CAM, Barker E, Reis D, Couto I, Cypriano C & de Oliveira IR. (2022). Family Aggression Screening Tool (FAST): factor structure and psychometric properties of subscales. Child Abuse & Neglect, 127, DOI: https://doi.org/10.1016/j.chiabu.2022.105548

Zou R, Boer OD, Felix JF, Muetzel R, Franken IHA, Cecil CAM & El Marroun H (in press). A neuroimaging study on maternal tobacco use during pregnancy and offspring brain morphology in preadolescence. JAMA Network Open.

2021

Bolhuis K, Steenkamp LR, Blanken LM, Neumann A, Jansen PR., Hillegers, MH, Cecil CAM, Tiemeier H & Kushner SA. (2021). Schizophrenia polygenic risk is associated with child mental health problems through early childhood adversity: evidence for a gene–environment correlation. European Child & Adolescent Psychiatry, 1-11. DOI: 10.1007/s00787-021-01727-4

Korologou-Linden R, Xu B, Coulthard E, Walton E, Wearn A, Hemani G et al. (2021). The bidirectional causal effects of brain morphology across the life course and risk of Alzheimers disease: A cross-cohort comparison and Mendelian randomization meta-analysis. medRxiv. DOI: 10.1101/2021.05.14.21256707.

Looman KIM, Cecil CAM, Grosserichter-Wagener C, Kiefte de Jong JC, van Zelm MC & Moll HA (2021). Associations between T cells and attention problems in the general pediatric population: the Generation R Study. JCPP Advances, e12038. DOI: 10.1002/jcv2.12038.

Luo M, Pappa I, Cecil CAM, Jansen P, van IJzendoorn MH & Kok R(2021). Maternal Psychological Problems During Pregnancy and Child Externalizing Problems: Moderated Mediation Model with Child Self-regulated Compliance and Polygenic Risk Scores for Aggression. Child Psychiatry Hum Dev. DOI: 10.1007/s10578-021-01154-1.

Luo M*, Meehan AJ*, Walton E, Roder S, Herberth G, Cosin M, Sunyer J, Mulder RH, Cortes Hidalgo AP, Bakermans-Kranenburg MJ, Felix JF, Relton C, Suderman M, Pappa I, Kok R, Tiemeier H, van IJzendoorn MH, Barker ED* & Cecil* CAM (2021). Neonatal DNA methylation and childhood low prosocial behavior: An epigenome-wide association meta-analysis. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. https://doi.org/10.1002/ajmg.b.32862

Mariani N*, Borsini A*, Cecil CAM, Felix JF, Sebert S, Cattaneo A….& Lekadir K (2021). Identifying Causative Mechanisms Linking Early-Life Stress to Psycho-Cardio-Metabolic Multi-Morbidity: The EarlyCause Project. PLOS ONE. DOI: 10.1371/journal.pone.0245475

Mulder RH, Neumann AH*, Cecil CAM*, Walton E, Houtepen LC…Suderman M (2021). Epigenome-wide change and variation in DNA methylation from birth to late adolescence. Human Molecular Genetics. DOI: 10.1093/hmg/ddaa280

Rijlaarsdam J., Barker ED., Caserini C., Koopman-Verhoeff ME., Mulder RH., Felix JF., & Cecil CAM. (2021). Genome-wide DNA methylation patterns associated with general psychopathology in children. Journal of Psychiatric Research. DOI: 10.1016/j.jpsychires.2021.05.029

Rijlaarsdam J, Cecil CAM, Buil M, van Lier P & Barker ED (2021). Exposure to bullying and general psychopathology: a prospective, longitudinal study. Research on Child and Adolescent Psychopathology. DOI: 10.1007/s10802-020-00760-2

Rijlaarsdam J, Cecil CAM, Relton CL & Barker ED (2021). Epigenetic Profiling of Social Communication Trajectories and Comorbid Psychiatric Conditions: A Prospective, Methylome-wide Association Study. Development and Psychopathology. DOI: 10.1017/S0954579420001662

Sammallahti S*, Cortes Hidalgo AP*, Tuominen S, Malmberg A, Mulder RH…& Cecil CAM*, Tiemeier H*, Lahti J* (2021). Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation. Molecular Psychiatry. DOI: 10.1038/s41380-020-00976-0

Warrier V, Kwong A, Luo M, Dalvie S, Croft J, Sallis H, Baldwin J, Munafo MR, Nievergelt CM, Grant AJ, Burgress S, Moore TM, Barzilay R, McIntosh A, van IJzendoorn MH, & Cecil CAM (2021). Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach. Lancet Psychiatry. DOI:https://doi.org/10.1016/S2215-0366(20)30569-1

2020

Caramaschi, D., Neumann, A., Cardenas, A., Tindula, G., Alemany, S., Zilich, L., … Cecil CAM & Sharp, G. (2020). Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills. bioRxiv. DOI: 10.1101/2020.12.18.423421

Cecil CAM, Zhang, Y. & Nolte T (2020). Childhood maltreatment and DNA methylation: A systematic review. Neuroscience & Biobehavioral Reviews. DOI: 10.1016/j.neubiorev.2020.02.019

Dall’Aglio L, Rijlaarsdam J, Mulder RH, Neumann A, Felix JF, Kok R, Bakermans-Kranenburg MJ, van IJzendoorn MH, Tiemeier H & Cecil CAM (2020). Epigenome-Wide Associations Between Observed Maternal Sensitivity and Offspring DNA Methylation: A Population-Based Prospective Study in Children. Psychological Medicine. DOI: 10.1017/S0033291720004353

Iob E, Schoeler T, Walton E, Cecil CAM, McQuillin A & Pingault JB (2020). Identifying risk factors involved in the common versus specific liabilities to substance use: A genetically informed approach. Addiction Biology. DOI: 10.1111/adb.12944

Knol MJ, Poot RA, Evans TE, Satizabal CL, Mishra A….& Adams, HH (2020). Genetic variants for head size share genes and pathways with cancer. Preprint. BioRxiv. DOI: https://doi.org/10.1101/2020.07.15.191114.

Koopman-Verhoeff ME, Mulder RH, Saletin JM, Reiss I, van der Horst GTJ, Felix JF, Carskadon MA, Tiemeier H & Cecil CAM (2020). Genome-wide DNA methylation patterns associated with sleep and mental health in children: A population-based study. Special Issue: Sleep and Mental Health. Journal of Child Psychology and Psychiatry. DOI: 10.1111/jcpp.13252

Mulder RH, Suderman M, Walton E, Neumann A, Houtepen LC, Rijlaarsdam J, Relton CL, Feliz JF, Tiemeier H, Bakermans-Kranenburg MJ, van IJzendoorn MH & Cecil CAM (2020). Epigenomics of being bullied: Changes in DNA methylation following bullying exposure. Epigenetics. DOI: 10.1080/15592294.2020.1719303

Neumann A*, Walton E*; Alemany S*, Cecil CAM, González JR, Jima DD, Lahti J, Tuominen ST, Barker E, Binder E, Caramaschi D, Carracedo A, Czamara D, Felix J, Fuemmeler BF, Gutzkow KB, Hoyo C, Julvez J, Kajantie E, Laivuori H, Maguire R, Maitre L, Murphy SK, Mason D, Murcia M, Raikkönen K, Sunyer J, Villa PM, Bakermans-Kranenburg M, van IJzendoorn M, Guxens M, Relton CL & Tiemeier H (2020). Associations between DNA methylation and ADHD symptoms from birth to school age: A meta-analysis study from the PACE consortium. Translational Psychiatry. DOI: 10.1038/s41398-020-01058-z

Thompson P & ENIGMA Working Group Chairs (2020). ENIGMA and Global Neuroscience: A decade of large-scale studies of the brain in health and disease across 40 countries. Translational Psychiatry. DOI: 10.1038/s41398-020-0705-1

Walton E, Calhoun V, Heijmans B, Thompson P & Cecil CAM (2020). The rise of neuroimaging epigenetics: A systematic review of studies examining associations between DNA methylation and brain imaging. Preprint. PsyArXiv. https://doi.org/10.31234/osf.io/4a8xn.

Zou R, El Marroun H, Cecil CAM, Jaddoe VWV, Hillegers M, Tiemeier H & White T (2020). Maternal Folate Levels During Pregnancy and Offspring Brain Development in Late Childhood. Clinical Nutrition. DOI: 10.1016/j.clnu.2020.11.025

2019

Bolhuis K, Viding E, Muetzel RL, El Marroun H, Kocevska D, White T, Tiemeier H & Cecil CAM (2019). Neural profile of callous traits in children: A population-based neuroimaging study. Biological Psychiatry. 85(5), 399-407. DOI: 10.1016/j.biopsych.2018.10.015

Caramaschi D, Hatcher C, Mulder R, Felix J, Cecil CAM, Relton C & Walton E (2019). Epigenome-wide association study of seizures in childhood and adolescence. Clinical Epigenetics. DOI: 10.1186/s13148-019-0793-z

Cecil CAM. Biopsychosocial pathways to mental health and disease across the lifespan: The emerging role of epigenetics (2019). I In W. Davies, Savulescu J and R. Roache (eds.). Psychiatry Reborn: Biopsychosocial psychiatry in modern medicine. Oxford University Press. DOI: 10.1093/med/9780198789697.001.0001

Dunn E, Nishimi K, Neumann A, Renaud A, Cecil CAM, Susser ES & Tiemeier E (2019). Time-dependent effects of exposure to physical and sexual violence on psychopathology symptoms in late childhood: In search of sensitive periods in development. Journal of the American Academy of Child and Adolescent Psychiatry. DOI: 10.1016/j.jaac.2019.02.022

Felix JF & Cecil CAM. Population epigenetics in the DOHaD framework (2019). Journal of Developmental Origins of Health and Disease. DOI: 10.1017/S2040174418000442

Mesirow SC, Cecil CAM, Maughan B, Jacka, FN & Barker ED (2019). Serum cholesterol, MTHFR methylation, and symptoms of depression in children. Developmental Psychology. DOI: 10.1037/dev0000831

Schoeler T, Choi SW, Dudbridge F, Baldwin J, Duncan L, Cecil CAM, Walton E, Viding E, McCrory E & Pingault JB (2019). Multi–Polygenic Score Approach to Identifying Individual Vulnerabilities Associated With the Risk of Exposure to Bullying. JAMA Psychiatry. DOI: 10.1001/jamapsychiatry.2019.0310

Koopman-Verhoeff ME, Bolhuis K, Cecil CAM, Kocevska D, Hudziak JJ, Hillegers MH, Mileva-Seitz VR, Reiss IK, Duijts L, Verhulst F, Luijk MP & Tiemeier H (2019). During Day and Night: Psychotic-Like Experiences associated with Nightmares in Childhood. Schizophrenia Research. DOI: 10.1016/j.schres.2018.12.002

Verhoeff ME, Serdarevic F, Kocevska D, Bodrij F, Mileva-Seitz VR, Jaddoe VWV, Hillegers MHJ, Tiemeier H, Cecil CAM, Verhulst F & Luijk MPC^†(2019). Pre-School Family Irregularity and the Development of Sleep Problems in Childhood: A Longitudinal Study. Journal of Child Psychology and Psychiatry. DOI: 10.1111/jcpp.13060

2018

Barker ED, Walton E & Cecil CAM (2018). Annual Research Review: DNA methylation as a mediator in the association between risk exposure and child and adolescent psychopathology. Journal of Child Psychology and Psychiatry, 59, 303–322. DOI: 10.1111/jcpp.12782

Barker ED, Cecil CAM, Walton E, Houtepen L, O’Connor TG, Danese A, Jaffee S, Jensen SKG, Pariante CM, McArdle W, Gaunt TR, & Relton C (2018). Inflammation-related epigenetic risk and child and adolescent mental health: A prospective study from pregnancy to mid-adolescence. Development and Psychopathology. 30(3), 1145-1156. DOI: 10.1017/S0954579418000330

Cecil CAM, Walton E, Pingault JB, Provencal N, Pappa I, Vitaro F, Cote S, Szyf M, Tremblay R, Tiemeier H, Viding E & McCrory EJ (2018). DRD4 methylation as a potential biomarker for physical aggression: An epigenome-wide, cross-tissue investigation. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. DOI: 10.1002/ajmg.b.32689

Cecil CAM, Walton E, Jaffee SR, O’Connor TG, Maughan B, Smith RG, Relton CL, McArdle W, Gaunt TR, Ouellet-Morin I & Barker ED (2018). Neonatal DNA methylation and early-onset conduct problems: A genome-wide, prospective study. Development & Psychopathology. 30(2):383-397. DOI: 10.1017/S095457941700092X

Dell’Aglio L, Muka T*, Cecil CAM*, Bramer WM, Verbiest MPJ, Nano J, Cortes Hildalgo A, Franco OH & Tiemeier H (2018). The role of epigenetic modifications in neurodevelopmental disorders: A systematic review. Neuroscience & Biobehavioural Reviews. DOI: 10.1016/j.neubiorev.2018.07.011

de Oliveira IR, Matos-Ragazzo AC, Zhang Y, Vasconcelos NM, Velasquez ML, Reis D, Ribeiro MG, da Rocha MM, Rosario MC, Stallard P & Cecil CAM (2018). Disentangling the mental health impact of childhood abuse and neglect: A replication and extension study in a Brazilian sample of high-risk youth. Child Abuse & Neglect. 80:312-323. DOI: 10.1016/j.chiabu.2018.03.021

Lim KX, Liu C, Schoeler T, Cecil CAM, Barker ED, Rijsdijk F, Viding E, Greven C & Pingault JB (2018). The role of birth weight on the causal pathway to child and adolescent ADHD symptomatology: A population-based twin differences longitudinal design. Special Issue on Developmental Pathways to Externalizing Psychopathology. Journal of Child Psychology and Psychiatry. DOI: 10.1111/jcpp.12949

Schoeler T, Duncan L, Cecil CAM , Ploubidis GB & Pingault JB (2018). Quasi-experimental evidence on developmental outcome s of bullying victimisation: A meta-analysis. Psychological Bulletin. doi: 10.1037/bul0000171. DOI: 10.1037/bul0000171

Zhang Y, Cecil CAM, Barker ED, Shigeyuki M & Lau J (2018). Dimensions of early adversity: Findings from a sample of Japanese institutionalized children. Child Psychiatry and Human Development. DOI: 10.1007/s10578-018-0850-4

2017

Barker ED, Cecil CAM, Walton E & Meehan A (2017). Genetic and gene-environment influences on disruptive behavior disorders. In J. Lochman and W. Matthys (eds.). The Wiley Handbook of Disruptive and Impulse-Control Disorders. New York: Wiley. Invited book chapter. DOI: 10.1002/9781119092254.ch8

Barker ED, Walton E, Cecil CAM, Jaffee SR, Rowe R, O’Connor TG, Maughan B, Stringaris A, Meehan A, McArdle W, Relton CL, & Gaunt TR (2017). A methylome-wide association study of trajectories of oppositional defiant behaviors and biological overlap with attention deficit hyperactivity disorder. Child Development. DOI: 10.1111/cdev.12957

Cecil CAM, McCrory EJ, Barker ED, Guiney J & Viding E (2017). Characterising youth with callous-unemotional traits and concurrent anxiety: Evidence for a high-risk clinical group. European Child & Adolescent Psychiatry. DOI: 10.1007/s00787-017-1086-8

Cecil CAM, Viding E, Fearon P, Glaser D & McCrory EJ (2017). Disentangling the mental health impact of child abuse and neglect. Child Abuse and Neglect. 63, 106–119. DOI: 10.1016/j.chiabu.2016.11.024

Meehan A, Maughan B, Cecil CAM, Barker ED (2017). Callous-Unemotional Traits and Co-Occurring Anxiety: Developmental Validity of an Adolescent Taxonomy. Journal of Abnormal Psychology.126(2): 225–236. DOI: 10.1037/abn0000235

Milaniak I, Cecil CAM, Barker ED, Relton CL, Gaunt TR, McArdle W & Jaffee SR (2017). Variation in methylation of the Oxytocin Receptor gene predicts children’s resilience to prenatal stress. Development and Psychopathology. DOI: 10.1017/S0954579417001316

Pingault JB, Cecil CAM, Murray J, Munafò MR, & Viding E (2017). Causal inference in psychopathology: Using Mendelian randomisation to identify environmental risk factors for psychopathology. Psychopathology Review. doi: http://dx.doi.org/10.5127/pr.038115.

Singham T, Viding E, Schoeler T, Arsenault L, Ronald A, Cecil CAM…Pingault JB (2017). Concurrent and longitudinal contribution of exposure to bullying in childhood to mental health: The role of vulnerability and resilience. JAMA Psychiatry. 74(11), 1112-1119. DOI: 10.1001/jamapsychiatry.2017.2678

Walton E, Cecil CAM, Suderman M, Liu J, Turner JA, Calhoun VD, Ehrlich S, Relton CL, & Barker, ED (2017). Longitudinal epigenetic predictors of amygdala:hippocampus volume ratio. Journal of Child Psychology and Psychiatry. DOI: 10.1111/jcpp.12740

2016

Cecil CAM, Smith RG, Walton E, Mill J, McCrory EJ & Viding E (2016). Epigenetic signatures of childhood abuse and neglect: Implications for psychiatric vulnerability. Journal of Psychiatric Research, 83, 184-194. DOI: 10.1016/j.jpsychires.2016.09.010

Cecil CAM, Walton E, Smith RG, Viding E, McCrory EJ, Relton CL, Suderman M, Pingault JB, McArdle W, Gaunt TR, Mill J & Barker ED (2016). DNA methylation and substance use risk: A prospective, genome-wide study spanning gestation to adolescence. Translational Psychiatry. 6(12), p.e976. DOI: 10.1038/tp.2016.247

Cecil CAM, Walton E & Barker ED (2016). Prenatal diet and childhood ADHD: The potential role of IGF2 methylation. Invited editorial. Epigenomics. 8(12):1573-1576. DOI: 10.2217/epi-2016-0131

Cecil CAM, Walton E & Viding E (2016). Epigenetics of addiction: Current knowledge, challenges and future directions. Journal of Studies on Alcohol and Drugs. 77(5), 688–691. DOI: 10.15288/jsad.2016.77.688

Mesirow M, Maughan B, Cecil CAM, Barker ED (2016). Associations between early-life fish and processed food intake, conduct problems, and co-occurring difficulties. Journal of Abnormal Child Psychology. 45(5):1039-1049. DOI: 10.1007/s10802-016-0224-y

Rijlaarsdam, J., Cecil CAM, Walton E, Mesirow MSC, Relton CL, Gaunt TR, McArdle W & Barker ED (2016). Prenatal unhealthy diet, IGF2 methylation and ADHD for early-onset conduct problem youth. Journal of Child Psychology and Psychiatry. DOI: 10.1111/jcpp.12589

Rijlaarsdam J, Pappa I, Walton E, Bakermans-Kranenburg M, Cecil CAM …Van Ijzendoorn, MH (2016). An epigenome-wide association meta-analysis of prenatal maternal stress in neonates: a model approach for replication. Epigenetics. DOI: 10.1080/15592294.2016.1145329

Walton E, Pingault JB, Cecil CAM, Gaunt TR, Relton CL, Mill J & Barker ED (2016). Epigenetic profiling of ADHD symptoms trajectories: A prospective, methylome-wide study. Molecular Psychiatry. DOI: 10.1038/mp.2016.85

2015

Cecil CAM, McCrory EJ, Viding E, Holden, GW & Barker ED (2015). Initial validation of a brief pictorial measure of caregiver aggression: The Family Aggression Screening Tool. Assessment. 23(3):307-20. DOI: 10.1177/1073191115587552

Cecil CAM, Viding E, McCrory EJ & Gregory A (2015). Distinct mechanisms underlie associations between forms of childhood maltreatment and disruptive nocturnal behaviours. Special Issue on pediatric sleep. Developmental Neuropsychology. 40(3):181-99. DOI: 10.1080/87565641.2014.983636

Cecil CAM, Walton E & Viding E (2015). DNA methylation, substance use and addiction: A systematic review from a developmental perspective. Current Addiction Reports. 2,331–346(2015). DOI: 10.1007/s40429-015-0072-9

Sebastian CL, De Brito S , McCrory EJ, Hyde ZH, Lockwood PL, Cecil CAM, & Viding E (2015). Grey matter volumes in children with conduct problems and varying levels of callous-unemotional traits. Journal of Abnormal Child Psychology. DOI: 10.1007/s10802-015-0073-0

2014

Cecil CAM, Lysenko LJ, Jaffee SR, Pingault JB, Smith RG, Relton CL, Woodward G, McArdle W, Mill J, & Barker ED (2014). Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: A 13-year longitudinal study. Immediate Communication. Molecular Psychiatry. Oct;19(10):1071-7. DOI: 10.1038/mp.2014.95

Cecil CAM, Viding E, Barker ED, Guiney J, & McCrory EJ (2014). Double disadvantage: The influence of childhood maltreatment and community violence exposure on adolescent mental health. Journal of Child Psychology and Psychiatry. DOI: 10.1111/jcpp.12213

Sebastian CL, McCrory EJ, Dadds M, Cecil CAM, Lockwood PL, Hyde Z, De Brito S & Viding E (2014). Neural responses to fearful eyes in children with conduct problems and varying levels of callous-unemotional traits. Psychological Medicine. 44(1), 99-109. DOI: 10.1017/S0033291713000482

2012

Cecil CAM, Barker ED, Jaffee SR, & Viding E (2012). Association between maladaptive parenting and child self-control over time: cross-lagged study using a monozygotic twin difference design. British Journal of Psychiatry. 201 (4), 291-297. DOI: 10.1192/bjp.bp.111.107581

Sebastian CL, McCrory EJ, Cecil CAM, Lockwood PL, De Brito S, Fontaine NMG, & Viding E (2012). Neural responses to affective and cognitive Theory of Mind in children with conduct problems and varying levels of callous-unemotional traits. JAMA Psychiatry. 69 (8), 814-822. DOI: 10.1001/archgenpsychiatry.2011.2070

Viding E, Sebastian CL, Dadds M, Lockwood PL, Cecil CAM, De Brito S, & McCrory EJ. (2012). Amygdala response to pre-attentive masked fear is associated with callous-unemotional traits in children with conduct problems. The American Journal of Psychiatry. 169 (10), 1109-1116. 10.1176/appi.ajp.2012.12020191

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